The Giallorossi took an early lead through Annamaria Serturini but soon fell behind, only for Andressa Alves to level things up early in the second half.
But the Bianconere finished strongly to claim all three points at a packed Stadio Tre Fontane, ending an eight-match winning streak for Alessandro Spugna's side.
Roma remain top of the standings as the league takes its winter break, with a three-point advantage over Juventus.
See more photos from the game in our gallery below.
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