Daniele De Rossi has put a slight injury concern behind him to be included for the game, while Francesco Totti is also over the toe injury that kept him out of Monday's trip to face Pescara.
Alessandro Florenzi remains the only long-term absentee.
Sunday's game gets underway at the Stadio Olimpico at 12:30 CEST.
AS Roma squad to face Lazio:
Alisson Becker
Bogdan Lobont
Wojciech Szczesny
Konstantinos Manolas
Emerson Palmieri
Mario Rui
Federico Fazio
Thomas Vermaelen
Bruno Peres
Juan Jesus
Antonio Rudiger
Gerson
Daniele De Rossi
Kevin Strootman
Diego Perotti
Clement Grenier
Radja Nainggolan
Leandro Paredes
Stephan El Shaarawy
Mohamed Salah
Edin Dzeko
Francesco Totti
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