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Ahead of the game, the Argentina international posted to Instagram to express his excitement about the impending contest.
"Sport creates the most amazing feeling when it unites people and I hope that will prove truer than ever tomorrow," Dybala wrote.
"It will be a game with so many emotions; to be returning to a city where I have so many friends and to play in a stadium where I enjoyed some great moments and celebrated winning trophies with Bianconeri fans who made me feel at home for seven years.
"This time, however, I will be playing for Roma - I will give everything I have to make the Giallorossi fans happy, amazing fans who have an incredible passion for the game and have welcomed me amazingly from the very first day.
"The beautiful thing about football is how all these things come together and that is why I want to enjoy this match.
"I am sure it will be an amazing spectacle ... and I will give everything to win it. Daje Roma!"
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