Coach Eusebio Di Francesco has a 21-man squad at his disposal for the match, which gets underway at 21:00 local time.
The winner of the game is guaranteed their place in the last-16 of the Champions League.
Manolas, who missed the weekend defeat to Udinese, came through a fitness test on Monday to be included in the squad.
Dzeko complained of a slight knock during the same training session; he is fit enough to be included in the matchday squad, with his condition to be re-assessed on Tuesday to determine the extent of his participation in the match.
See the full squad in the graphic below.
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