Roma have won four of their last 13 Serie A encounters with Sampdoria. The Blucerchiati have won five and there have been four draws.
Luis Muriel has found the net four times in seven league matches against Roma – more than he's scored against any other team.
Roma have played seven times on 11 September, collecting three wins and four defeats. The Giallorossi's last victory on this date was in 1994: 1-0 away to Inter.
Sampdoria are one of 13 teams Luciano Spalletti has never lost to as a coach. With Spalletti in the Roma dugout, the Genoa-based outfit have lost four times and drawn once.
Francesco Totti is Roma's all-time highest scorer against Sampdoria on 14 goals. He's followed by Pedro Manfredini (eight), then Dino Da Costa and Abel Balbo (both seven).
Roma have hosted Sampdoria 58 times for a league fixture prior to this weekend. The Giallorossi have won 37, drawn 12 and lost nine.
A win against Sampdoria would take Luciano Spalletti past the 200-point mark in home league games. The coach has earned 198 points on home soil before Sunday's match.
Roma v Sampdoria will be Luciano Spalletti's 250th game as Giallorossi boss. He has recorded 139 wins, 59 draws and 53 defeats across his two stints in the capital.
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