
The Italy international does not start the game after suffering a back injury while on international duty, with Radja Nainggolan both captaining the side and slotting into midfield in his absence.
Spalletti has opted for an attack featuring Mohamed Salah, Stephan El Shaarawy and Edin Dzeko.
The Giallorossi need to score at least twice if they are to reach the final.
See the full line-up in the graphic below.
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