The Argentine defender will skip the away game as a precautionary measure, after failing to fully recover from a slight knock he sustained at the end of Wednesday's Champions League draw with Chelsea.
But both Schick and Defrel are available to travel, after missing a number of games with injury.
Sunday's game at Turin's Stadio Olimpico gets underway at 15:00 CEST.
See the full squad list below.
Alisson Becker
Bogdan Lobont
Lukasz Skorupski
Juan Jesus
Aleksandar Kolarov
Hector Moreno
Bruno Peres
Rick Karsdorp
Leandro Castan
Radja Nainggolan
Kevin Strootman
Lorenzo Pellegrini
Daniele De Rossi
Maxime Gonalons
Alessandro Florenzi
Gerson
Diego Perotti
Edin Dzeko
Cengiz Under
Gregoire Defrel
Patrik Schick
Stephan El Shaarawy
Mirko Antonucci
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