Luciano Spalletti has never lost to Napoli in either of his spells as Roma coach. The Tuscan has met the Partenopei on seven occasions in the past in all competitions and his record reads as follows: five wins, two draws, 16 for and six against. What's more, Spalletti has a 100% record at the Stadio San Paolo. He has three victories from as many trips south - all with clean sheets: a 3-0 success in the 2005 Coppa Italia plus wins in 2008 (2-0) and 2009 (3-0).
Dino Da Costa's eight goals in this fixture make him Roma's all-time leading marksman in matches against Napoli in all competitions. Francesco Totti is just one behind the Brazilian centre forward, while Amedeo Amadei and Pedro Manfredini both struck half a dozen against the Azzurri.
Roma have scored a league high 11 goals in the second halves of matches this season.
Mohamed Salah has already set up Edin Dzeko for eight chances this season, while the Bosnian has returned the favour four times. Their dozen combined efforts make them Serie A's most creative partnership.
All but two of Roma's 16 league goals this term have come from their forwards, more than any other side. Napoli follow with 10.
With 16 and 14 goals scored respectively, Roma and Napoli boast the most prolific and third best strikeforces in the Italian top flight.
Dzeko has more shots (40) and efforts on target (20) than any other player in Serie A this season.
Victory for Spalletti's side would see Napoli become the fifth team that Roma have beaten at least 50 times in Serie A as a single division.
The two teams have met 142 times in Italy's top flight. Roma have won 50, lost 41 and drawn 51.
The Giallorossi have had more shots (145) in Serie A this season than anyone else. Napoli, meanwhile, have the highest ball possession average (60%).
It's 275 minutes since Napoli last found the net against Roma in the league. Jose Callejon scored way back in November 2014.
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