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The Foxes travel to Rome for the game at the Stadio Olimpico (21:00 CEST) after a 1-1 draw in Leicester in last week's first leg, as both sides battle to reach the May 25 final in Tirana, Albania.
And Rodgers has acknowledged this is his side's biggest contest of the campaign.
"He's coming through well, so he's okay for the game," Rodgers said, when asked about Vardy's fitness.
"[Maddison and Dewsbury-Hall] are okay. They trained yesterday and came through well."
After an injury-hit season, Rodgers feels his squad are in good shape heading into the showdown.
"Everyone [else] is available and ready," he said.
"These last weeks, we’ve been getting players back. But I still had to manage the group in order to get to this point. With all the games, we had the risk of getting to a semi-final with some of our best players unavailable.
"That was a risk that, for me, would be too much really. That was the idea of making the changes. Ideally, we wouldn’t be making so many, but we’re having to nurse the players through to the big games and this is our biggest game of the season.
"We arrive into it with players fit, ready and fully focused.
"We're ready to take on the challenge. It’s a much healthier position than what we’ve been in for most of the season."
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