The Giallorossi, leading 1-0 from last week's first leg in the Netherlands, fell behind to Vitesse Arnhem midway through the second half - as Maximilian Wittek lashed home an impressive volley to level the tie.
Extra-time appeared to therefore be becoming; at least until Abraham delivered his seventh goal of the competition so far as he latched onto substitute Rick Karsdorp's cutback and finished.
Jose Mourinho's side are thus into the draw for the last-eight of the competition - which takes place in Nyon on Friday afternoon.
ROMA 1-1 VITESSE
(2-1 on aggregate)
GOALSCORERS: Abraham (90'); Wittek (62’)
ROMA (3-4-1-2): Rui Patricio; Ibanez, Smalling, Kumbulla; Maitland-Niles (Karsdorp), Veretout (Cristante), Mkhitaryan, Vina (El Shaarawy); Pellegrini (Bove); Zaniolo (Afena-Gyan), Abraham
VITESSE (4-4-2): (4-4-2): Houwen; Dasa, Doekhi, Rasmussen, Wittek; Tronstad, Bazoer (Buitink), Domgjoni (Frederiksen); Huisman (Gboho); Grbic, Openda
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