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First half goals from Sergio Reguilon and Youssef En-Neysri decided the game for the Spanish side. Gianluca Mancini was sent off for the Giallorossi in the closing stages.
In the one-off game at Duisburg's MSV-Arena, Paulo Fonseca's side seemed to struggle out of the blocks - with Jules Kounde heading against the bar early on. Once Reguilon had glided into the box and finished under Pau Lopez, however, it always looked an uphill battle.
En-Neysri's finish after fine work from Lucas Ocampos came just before the half-time break, further enhancing Sevilla's control over the match.
Roma briefly threatened in the second half, but were ultimately unable to find the goal they needed to set up a tense finale.
The result brings an end to the season for the Giallorossi, who will now look ahead to the 2020-21 campaign.
Imperium Partners
Centurion Partners
