The World Cup winner, a summer signing from Sevilla, is included in Eusebio Di Francesco's squad list for the first time as a Giallorossi player - and could yet make his bow in front of the Giallorossi fans at the Stadio Olimpico.
Di Francesco confirmed in his pre-match press conference that another summer arrival, Bryan Cristante, is "almost certain" to make his first start for the club in the game.
Elsewhere, Diego Perotti is still unavailable through injury - while Kevin Strootman is absent.
See the full squad below.
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