The match at the Stadio Olimpico gets underway at 20:30 local time.
Di Francesco acknowledged in his pre-match press conference that neither Argentine will be fit to start against the Nerazzurri, but nevertheless he has Perotti and Pastore back as potential options from the bench.
With the likes of Stephan El Shaarawy, Lorenzo Pellegrini and Edin Dzeko sidelined, however, Primavera youngsters Zan Celar and Alessio Riccardi have been added to the 21-man matchday group.
See the full list in the graphic below.
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