Genoa have only won once this term without Diego Perotti and Leonardo Pavoletti. The pair are both suspended for the Roma game. They have lost all of the other seven matches in which the duo were missing, scoring just three goals in that time.
Alessandro Florenzi has scored twice against Genoa, including in the last Serie A fixture between the two sides at the Olimpico. He has only scored more in Serie A against Bologna (three).
Rudi Garcia has won three of his four matches against Gian Piero Gasperini's Genoa without conceding. The Rossoblu coach's only win was the 1-0 victory at the Ferraris in May 2014.
Four of Roma's last five goals have come from dead-ball situations. Two were scored by Miralem Pjanic (one penalty, one direct free-kick) and two by Edin Dzeko (both spot-kicks).
Roma have won six of their last seven meetings with Genoa in Serie A. The only win for the Rossoblu came at the Marassi in May 2014.
The Giallorossi have won their last nine home league matches against Genoa, scoring 24 goals in that time at an average of 2.7 per game.
Roma have scored the most goals in Serie A from set-pieces this season (12), while no team has conceded as many as Genoa (10) from dead-ball situations.
The latest player to represent both sides is Iago Falque, who hit 13 goals in 32 league appearances for Genoa last season.
In their first 16 league games of every season since 1994-95, only once have Genoa scored fewer goals than their tally of 15 this term. They only managed 13 in 2010-11.
Genoa and Roma are the two teams who have conceded the fewest goals in the opening 30 minutes of games this season (just two each).
Miralem Pjanic has had a hand in 40% of the Giallorossi's league goals, courtesy of his seven strikes and five assists.
Roma have a goal difference of +70 from their matches against Genoa in the capital. The Giallorossi have struck 95 times in 48 games in the Eternal City, conceding 25.
Roma and Genoa have met 96 times in the top flight. Roma's record reads 43 wins, 21 draws and 32 defeats.
Radja Nainggolan is set to make his 200th Serie A appearance.
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